For laboratory research use only — not for human or veterinary use. Not evaluated by the U.S. FDA.
Neuropeptide
PE-22-28
A seven-amino-acid peptide derived from the spadin sequence, studied in animal models as a TREK-1 channel blocker in neuroplasticity research.
Quantity
$39.99
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Delivery
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Cutoff 3:00 PM ET · same-day dispatch
Estimated arrival in 2–3 business days
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Free shipment protection included
PE-22-28
1 × 10mg · $39.99
99% purity, QC passed
HPLC + mass-spec verified
Shipment protection
Free on every order
Free shipping over $150
Same-day dispatch before 3PM ET
Certificate of Analysis
Third-party tested · Independent analytical lab
10mg
99.75%latest
| Tested | Measured | Purity |
|---|---|---|
| Jun 2026 | 12.86mg | 99.75% |
| Jan 2026 | 11.81mg | 99.81% |
Frequently researched together
Commonly studied alongside PE-22-28.
Compound information
Technical specifications
Storage & stability
- ❄️
Lyophilized (powder)
-20°C · stable 2+ years
- ❄️
Reconstituted
2–8°C · use within 30 days
Sources & references
Peer-reviewed literature, for research context
- Frontiers in pharmacology
Shortened Spadin Analogs Display Better TREK-1 Inhibition, In Vivo Stability and Antidepressant Activity
2017·DOI: 10.3389/fphar.2017.00643·PMID: 28955242Djillani A, Pietri M, Moreno S, Heurteaux C, Mazella J, Borsotto M
View source - PLoS biology
Spadin, a sortilin-derived peptide, targeting rodent TREK-1 channels: a new concept in the antidepressant drug design
2010·DOI: 10.1371/journal.pbio.1000355·PMID: 20405001Mazella J, Pétrault O, Lucas G, Deval E, Béraud-Dufour S, Gandin C
View source - Neuropharmacology
Spadin as a new antidepressant: absence of TREK-1-related side effects
2012·DOI: 10.1016/j.neuropharm.2011.07.019·PMID: 21807005Moha Ou Maati H, Veyssiere J, Labbal F, Coppola T, Gandin C, Widmann C
View source
Important research notice
Not for human consumption. This product is sold exclusively for laboratory and in vitro research. It is not intended to diagnose, treat, cure, or prevent any disease.
Any research findings referenced on this page are drawn from published, peer-reviewed literature and are provided for educational context only. They are not product claims and should not be read as medical advice.
By purchasing, you confirm you are a qualified researcher and will handle this material in accordance with all applicable laws and institutional guidelines.