For laboratory research use only — not for human or veterinary use. Not evaluated by the U.S. FDA.
Metabolic Peptide
5-Amino-1MQ
A small-molecule NNMT inhibitor investigated in metabolic research for its influence on the NAD+ salvage pathway and cellular lipid handling in preclinical models.
Size
Quantity
$39.99
Bundle & save
Delivery
Order by 3:00 PM ET for same-day dispatch
Cutoff 3:00 PM ET · same-day dispatch
Estimated arrival in 2–3 business days
Overnight shipping available
Free shipment protection included
5-Amino-1MQ
1 × 5mg · $39.99
99% purity, QC passed
HPLC + mass-spec verified
Shipment protection
Free on every order
Free shipping over $150
Same-day dispatch before 3PM ET
Certificate of Analysis
Third-party tested · Independent analytical lab
50mg
| Tested | Measured |
|---|---|
| Jul 2026 | 61.22mg |
| May 2026 | 60.69mg |
| May 2026 | 60.45mg |
| Apr 2026 | 59.83mg |
| Mar 2026 | 57.17mg |
| Feb 2026 | 57.83mg |
| Dec 2025 | 57.18mg |
| Dec 2025 | 57.50mg |
| Nov 2025 | 58.75mg |
| Oct 2025 | 55.75mg |
Frequently researched together
Commonly studied alongside 5-Amino-1MQ.
Compound information
Technical specifications
Molecular profile
| Type | Small molecule NNMT inhibitor |
| CAS number | 42464-96-0 |
| Molecular weight | 159.21 g/mol (cation) |
| Formula | C10H11N2+ |
Storage & stability
- ❄️
Lyophilized (powder)
-20°C · stable 2+ years
- ❄️
Reconstituted
2–8°C · use within 30 days
Sources & references
Peer-reviewed literature, for research context
- Journal of Medicinal Chemistry
Structure-Activity Relationship for Small Molecule Inhibitors of Nicotinamide N-Methyltransferase
2017·DOI: 10.1021/acs.jmedchem.7b00389·PMID: 28548833Neelakantan H, Wang HY, Vance V et al.
View source - Biochemical Pharmacology
Selective and membrane-permeable small molecule inhibitors of nicotinamide N-methyltransferase reverse high fat diet-induced obesity in mice
2018·DOI: 10.1016/j.bcp.2017.11.007·PMID: 29155147Neelakantan H, Vance V, Wetzel MD et al.
View source - Biochemical Pharmacology
Small molecule nicotinamide N-methyltransferase inhibitor activates senescent muscle stem cells and improves regenerative capacity of aged skeletal muscle
2019·DOI: 10.1016/j.bcp.2019.02.008·PMID: 30753815Neelakantan H, Brightwell CR, Graber TG et al.
View source - Scientific Reports
Combined nicotinamide N-methyltransferase inhibition and reduced-calorie diet normalizes body composition and enhances metabolic benefits in obese mice
2021·DOI: 10.1038/s41598-021-85051-6·PMID: 33707534Sampson CM, Dimet AL, Neelakantan H et al.
View source - Journal of Pharmaceutical and Biomedical Analysis
Development & validation of LC-MS/MS assay for 5-amino-1-methyl quinolinium in rat plasma: Application to pharmacokinetic and oral bioavailability studies
2021·DOI: 10.1016/j.jpba.2021.114255·PMID: 34304009Awosemo O, Neelakantan H, Watowich S et al.
View source - Journal of Obstetrics and Gynaecology
Small molecule inhibitor of nicotinamide N-methyltransferase shows anti-proliferative activity in HeLa cells
2021·DOI: 10.1080/01443615.2020.1854696·PMID: 33645410Akar S, Duran T, Azzawri AA et al.
View source - Scientific Reports
Reduced calorie diet combined with NNMT inhibition establishes a distinct microbiome in DIO mice
2022·DOI: 10.1038/s41598-021-03670-5·PMID: 35013352Dimet-Wiley A, Wu Q, Wiley JT et al.
View source - Diabetes, Obesity and Metabolism
Nicotinamide N-methyltransferase inhibition mitigates obesity-related metabolic dysfunction
2024·DOI: 10.1111/dom.15879·PMID: 39161060Babula JJ, Bui D, Stevenson HL et al.
View source
Important research notice
Not for human consumption. This product is sold exclusively for laboratory and in vitro research. It is not intended to diagnose, treat, cure, or prevent any disease.
Any research findings referenced on this page are drawn from published, peer-reviewed literature and are provided for educational context only. They are not product claims and should not be read as medical advice.
By purchasing, you confirm you are a qualified researcher and will handle this material in accordance with all applicable laws and institutional guidelines.