For laboratory research use only — not for human or veterinary use. Not evaluated by the U.S. FDA.
Peptide Bioregulator
Vilon
A synthetic dipeptide from the Khavinson bioregulator series, among the most-studied of the group in preclinical models of thymic and immune-tissue signaling.
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Vilon
1 × 20mg · $59.99
99% purity, QC passed
HPLC + mass-spec verified
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About Vilon
Structure and research context
Vilon is a synthetic dipeptide with the sequence Lys-Glu (L-lysyl-L-glutamic acid, KE; formula C11H21N3O5, molecular weight 275.30 g/mol, CAS 45234-02-4). It pairs a basic lysine with an acidic glutamic acid residue and is one of the shortest compounds in the Khavinson bioregulator series. Much of its published literature concerns thymocytes and other immune cells, gene expression profiling and modeled interactions between the dipeptide and DNA.
Vilon in the research literature
In mouse thymocytes, Vilon produced a comitogenic effect on proliferation and stimulated sphingomyelinase activity in thymocyte membranes, more strongly than Ala-Glu-Asp-Gly or Ala-Glu-Asp-Pro in the same comparison. In mouse splenocytes in vitro, it activated interleukin-2 mRNA synthesis in the absence of specific inductors.
A cDNA microarray study of mouse heart tissue reported that Vilon changed the expression of 36 of 15,247 clones. In mesenchymal stem cell cultures, KE increased SIRT1 gene expression and protein synthesis and reduced PARP1 and PARP2 expression in late-passage cells, and molecular modeling proposed KE binding to GC-rich double-stranded DNA sequences found in the promoters of these genes.
Summarized from peer-reviewed literature for research context only; not a product claim. PubMed: 12420072 · 12447482 · 12360356 · 37782636
Vilon Certificate of Analysis
Third-party tested · Independent analytical lab
20mg
99.13%latest
| Tested | Measured | Purity |
|---|---|---|
| Oct 2025 | 20.56mg | 99.13% |
Frequently researched together
Commonly studied alongside Vilon.
Compound information
Technical specifications
Molecular profile
| Type | Synthetic dipeptide bioregulator |
| CAS number | 45234-02-4 |
| Molecular weight | 275.30 g/mol |
| Amino acids | 2 |
| Sequence | Lys-Glu |
| Formula | C11H21N3O5 |
Storage & stability
- ❄️
Lyophilized (powder)
-20°C · stable 2+ years
- ❄️
Reconstituted
2–8°C · use within 30 days
Vilon sources & references
Peer-reviewed literature, for research context
- Doklady biological sciences : proceedings of the Academy of Sciences of the USSR, Biological sciences sections
A synthetic dipeptide vilon (L-Lys-L-Glu) inhibits growth of spontaneous tumors and increases life span of mice
2000·PMID: 10944717Khavinson VKh, Anisimov VN
View source - Bulletin of experimental biology and medicine
Effect of vilon on biological age and lifespan in mice
2000·DOI: 10.1007/BF02682106·PMID: 11140587Khavinson VK, Anisimov VN, Zavarzina NY, Zabezhinskii MA, Zimina OA, Popovich IG
View source - Bulletin of experimental biology and medicine
Studies of the effects of Vilon and Epithalon on gene expression in mouse heart using DNA-microarray technology
2002·DOI: 10.1023/a:1015859322630·PMID: 12360356Anisimov SV, Bokheler KR, Khavinson VKh, Anisimov VN
View source
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Important research notice
Not for human consumption. This product is sold exclusively for laboratory and in vitro research. It is not intended to diagnose, treat, cure, or prevent any disease.
Any research findings referenced on this page are drawn from published, peer-reviewed literature and are provided for educational context only. They are not product claims and should not be read as medical advice.
By purchasing, you confirm you are a qualified researcher and will handle this material in accordance with all applicable laws and institutional guidelines.